KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K3
All Species:
13.64
Human Site:
T48
Identified Species:
25
UniProt:
P46734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46734
NP_002747.2
347
39318
T48
P
R
N
L
D
S
R
T
F
I
T
I
G
D
R
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
A52
Q
Q
R
K
R
L
E
A
F
L
T
Q
K
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546666
347
39324
T48
P
R
N
L
D
S
R
T
F
I
T
I
G
D
R
Cat
Felis silvestris
Mouse
Mus musculus
O09110
347
39278
T48
P
R
N
L
D
S
R
T
F
I
T
I
G
D
R
Rat
Rattus norvegicus
Q4KSH7
419
47517
G104
Q
E
I
M
K
Q
T
G
Y
L
T
I
G
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511595
352
40240
T53
P
R
N
L
D
S
R
T
F
I
T
I
G
D
K
Chicken
Gallus gallus
Q90891
398
44059
A54
Q
Q
K
K
R
L
E
A
F
L
T
Q
K
A
K
Frog
Xenopus laevis
Q07192
446
50082
K133
H
S
I
E
S
S
G
K
L
K
L
S
P
E
Q
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
A64
P
R
D
L
D
S
K
A
Y
V
T
I
G
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477162
334
38176
A43
D
R
T
F
D
I
D
A
D
S
L
E
K
I
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
L50
R
S
L
S
T
G
T
L
K
Y
P
D
D
E
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
R54
T
S
D
E
K
Q
S
R
Q
S
D
S
K
E
L
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
G344
K
L
S
L
S
S
K
G
I
D
F
S
N
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.7
N.A.
99.1
N.A.
96.5
37.2
N.A.
89.7
30.3
42.1
75.3
N.A.
57
N.A.
37.7
N.A.
Protein Similarity:
100
47
N.A.
99.7
N.A.
98.8
56.7
N.A.
93.1
48.7
58
84.4
N.A.
72.9
N.A.
55.6
N.A.
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
20
N.A.
93.3
13.3
6.6
53.3
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
46.6
N.A.
100
33.3
20
93.3
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
31
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
16
0
47
0
8
0
8
8
8
8
8
31
0
% D
% Glu:
0
8
0
16
0
0
16
0
0
0
0
8
0
31
0
% E
% Phe:
0
0
0
8
0
0
0
0
47
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
8
16
0
0
0
0
47
16
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
16
0
0
8
0
0
8
31
0
47
0
8
0
% I
% Lys:
8
0
8
16
16
0
16
8
8
8
0
0
31
0
31
% K
% Leu:
0
8
8
47
0
16
0
8
8
24
16
0
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
31
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
39
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% P
% Gln:
24
16
0
0
0
16
0
0
8
0
0
16
0
8
16
% Q
% Arg:
8
47
8
0
16
0
31
8
0
0
0
0
0
0
24
% R
% Ser:
0
24
8
8
16
54
8
0
0
16
0
24
0
0
8
% S
% Thr:
8
0
8
0
8
0
16
31
0
0
62
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _